I have never heard of this treatment. How long has it been in use? Explain it further if able. I have had IC for 32 years. I have had DSMO instillations, several, and am now trying Elmiron. I am in less pain, but still have spasms and frequency. I have been taking Elmiron since Sept. Has anyone else had much success on it. I would be interested from hearing from women who have had IC for many years and anything that they have found beneficial.