If you are on coumadin, then you must be followed by a doctor regularly to check your Protime to sdjust the dosage if necessary. This doctor is the one to answer your questions. I had tooth transplantation and I did have to stop coumadin a few days before the procedure, and resumed immediately after. But again, your doctor is the one to determine the timing. If you are not under doctor's care for the coumadin, you should be ; wrong dosage can be very harmful.