Talk to your husbands doctor right away.. There are many alternative medications for depression and sometimes it takes a while to find the correct med and proper doseage. I tried 2 other meds before I found the one that is perfect for me. Don't give up! Explain to his doctor that the current med is not doing it's job and acurately discribe the symptoms. You may need to consult with a medication management specialist or a physciatrist who is more familiar with the alternatives. Don't give up - there is help out there!