Leslie I started the 6MP about 3 weeks ago and it seems to be helping me. I am on prednisone, asacol, and the 6MP. I started on 60 m.g. of prednisone and now I am tapering off to 40mg. as of tomorrow. Once I get down to 20mg. the Doc wants to give me a full colonoscopy. I really want to have this done so I know what is going on. The 6MP did not give me any horrible side affects like the prednisone did. So you may want to try it. Good Luck Joe D.