I am a 45 yr old female and experiencing an irregular menstrual cycle from time to time ever since but the irregularity is more prominent from the last three years- from delayed 1 week to almost a month. Like now I am delayed for over 1 1/2 month. I am experiencing a lot of mental, emotional stress for the last couple of years...I don't know how to asses if that was a chronic stress as I have known that can cause cessation of menstrual cycles too. I have tested negative two times one week apart on over the counter pregnancy test last couple of weeks. My weight is just about right did'not change abruptly I am 5'4 120 lbs. I accumulated about 4 lbs from 8 mos. ago I am 116 to 117lbs ussually. I don't know if there is a possibility that I am pregnant though I don't feel like and there is no systoms....I had three children 8,9 and 11yrs old. Is this an early sign of menopause? I had a history of irregular menstrual period even when I am younger couple of times it will stop one month. And I have my period so long at least 10 days ...first five days heavy and the rest sometimes heavy sometimes not until it slowly fades but I will see stain until at leat another 5 days after that 10 days that the menstrual blood is coming out. Is there any possibility of pregnancy of any kind(tubular or ?) or any tumor existing? Bec. it could sometime reads not pregnant bec. of a pathology inside. How accurate is the over the counter pregnancy test? I will not have a doctor's appointment not until 10 days.