Can IC cause lower back pain. It feels like I have razor blades in my bladder with constant burning. Can anyone relate. I am taking prozac and atarax for 5 days feel no relief only yawn and feel tired. I am a professional and can't stay focused with my patients. Can you get pain down the leg. I took extensive antiobiotic therapy. Can that cause IC. Is it possible I have yeast and not IC or autoimmune problems. My body feels chronically tired. Appreciate a response.