I do not suffer from depression but I do suffer from back problems and whenever I get sick my back symptoms flair up. I can be fine but when I get sick the back gets worse. When I recover from the cold the back flairs down and gets better. I think because of hormone fluctuation but I am not sure. I do not know if this is true for depression too, but I would think it would be. Ask your doctor next time you visit him/her. They should be able to help.