It can be very frustrating when the Dr.'s say there's nothing wrong. Don't give up! I went thru the same thing w/ IBS and Fibromyalgia at 2 different times in my life. The biggest thing you can do for your husband is be there for "support". Keep going to different Dt.'s until you find one that will diagnose him. If you haven't been - a Gasternologist is a good place to go for IBS. The best of luck to you and your husband. Hope this has helped some.