Hi, I have had a few liber biopsy done. I had them done before my transplant and had one done since. They really are the easiest of all I think. They numb the area and insert a needle with a grip on the end. They pinch a piece of the liver and that is it. The most important thing is afterwards. You have to lay still for a couple of hours and have to have someone drive you home. You will be fine. Good luck.