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I have been suffering from Piraformis Syndrome since May of 2000 and have tried all traditional forms of treatment. Although I have seen some improvement, this condition has completely altered my lifestyle. I want very much to be pain free. This conditioned is very much affected by stress and too much physical activity (walking, biking, rollerblading, sitting, etc.). I recently read about someone having botox injections into the piraformis muscle and getting some very good results. Has anyone had this experience and if so, are there any side affects, can the injections be harmful, did you get good results, etc. I would appreciate any information that anyone can provide me.