Dear S.Cardwell, Your story sounds the same as mine. I am 42 and was misdiagnosed with JRA at age 10. Was correctly diagnosed with AS about 10 years ago. 1st thing they put me on was Indocin. Took the pain away almost immediately but then developed side effects of migraine and nausea. Have gone through many meds since then but have found some relief with Celebrex. Also easy on stomach. If you'd like to correspond any further, I'll post my email address.