Hi Mike, my name is Teri and I swore that I would NEVER let them do a liver biopsy on me because it sounded too gross. Last December I finally grit my teeth and had it, and it was not bad at all! It's just scary, and I am a big chicken and hate pain. It only takes a few seconds and after the general numbing of the outside skin, which burns a little, it is really fast. Like Nike says, just do it!