Chronic fatigue syndrome is often diagnosed as merely a SYMPTOM of genetically inherited depression. CFS can often be treated successfully with an anti-depressant. Fortuneately today we have a variety of anti-depressants to choose from. See a good psychiatrist and ask him specifically for an anti-depressant. Don't give up on the idea of an anti-depressant, even if the first one does not work well or for a lenghthy period. Your shrink should know the proper one from your precise symptoms.