I've had Crohn's disease for about 35 years and have found limited relief from symptoms during this time despite 5 surgeries. Recently I happened upon MSM and have found a very positive synergy between it, dipentum and Vit C. I'm using 500 mg of dipentum three times a day with 1.5 gms of MSM 3 times a day and about 1 gm of vit C split into 3-4 doses. I'm currently totally free of symptoms for the frist time in my life. If you suffer from Crohn's it's worth a try. Walmart sells MSM for a very reasonable price - 120 capsules for about $7. Please let me know if you try this and what happens.