Learning to cope with any debilitating disease is a true challenge, but the number one most important thing is finding the right doctor....someone who will work with you and for you. Next would be finding the right medication or medication combination that is right for you. And last, don't give in to the disease of AS but fight back with exercise, exercise, exercise! It hurts a great deal and you may not feel up to doing it, yet the end results are worth it...you will have more energy and your outlook on life will be better. Take care and I hope this helps.