have you contacted the research center in Denver CO.? Also, have they tried the senory of brushing? Found that my son who is 3 does better with private therapy of speech and ot then in school. He does have behavior problems in school, but at home ok. My son gets to throwing, pulling hair when sleepy or upset. He is does not take meds. Cant offer really any advice that you may already know, but did take mine to psy. to see if he had ADD or ADH and would not see him she was not familuar with Frigle x. So I can offer is contact Denver childrens hospital, fragile x research department and talk with them. They do offer evaluations. Hope this does help.